Preheat the oven to 350°F. Grease a 9x13-inch baking dish with olive oil.
In a large mixing bowl, combine the cooked rotini pasta, shredded chicken, broccoli florets, Alfredo sauce, garlic powder, Italian seasoning, salt, and pepper. Mix until all ingredients are well combined.
Transfer the mixture to the prepared baking dish, spreading it evenly. Sprinkle the shredded mozzarella and grated Parmesan cheese over the top. If desired, add breadcrumbs for an extra crunchy topping.
Cover the baking dish with aluminum foil and bake in the preheated oven for 25 minutes.
Remove the foil and bake for an additional 10-15 minutes, or until the cheese is bubbly and golden brown.
Let the dish cool for about 5 minutes before serving.